Bioequivalence and Bioavailability Forum • high fat breakfast intake

high fat breakfast intake [Design Issues]

posted by jag009 – NJ, 2013-05-31 17:43 (4773 d 13:19 ago) – Posting: # 10703
Views: 4,747

Hi Susanta,

❝ Therefore it is recommended to take test medication after 30 minutes of the high-fat breakfast for uniform mixture of food particles in stomach for »absorption... Hence, if subject will take food in sequential order or »not, it will not effect the drug absorption in stomach as test drug will »take after 30 minutes of high-fat breakfast. :-)

Maybe I am reading it wrong but from your post it seems like subjects had to wait for 30mins after completing their meal before drug administration? From the protocols I have seen, all stated that subjects have 30 mins to eat the breakfast prior to dosing (ie: meal starts at 8:30AM, dosing at 9AM)-> Meaning they can finish anytime before 9AM.

Thanks
John

Complete thread:

high fat breakfast intake jag009 2013-05-24 17:09
- high fat breakfast intake ElMaestro 2013-05-24 18:07
- high fat breakfast intake susanta 2013-05-28 11:28
  - high fat breakfast intakejag009 2013-05-31 15:43
    - high fat breakfast intake Susanta 2013-05-31 17:40
- high fat breakfast intake sarada06884 2013-05-29 08:44
- high fat breakfast intake luvblooms 2013-05-31 14:28