Bioequivalence and Bioavailability Forum • randomization: runs test? validation?

randomization: runs test? validation? [Regulatives / Guidelines]

posted by d_labes – Berlin, Germany, 2012-06-16 15:10 (5126 d 02:30 ago) – Posting: # 8753
Views: 15,522

Dear Helmut!

Q1: What is the rationale behind using the runs test :confused:

.
What did a randomisation based on this achieve extra compared to a randomization using lots, a hat and a NLYW dancing around it while drawing from the lots?

Q2: What can we do in validating a randomisation software or hardware as described above?
Remember your nice own post of a scene from Dilbert's life.
[image]

—
Regards,

Detlew

Complete thread:

USFDA requirement for randomization Ravi 2012-06-15 13:39
- randomization: validation Helmut 2012-06-15 17:39
  - randomization: runs test? validation?d_labes 2012-06-16 13:10
    - randomization: runs test? validation? Helmut 2012-06-16 14:00
      - probability nearly zero? d_labes 2012-06-16 16:11
        
        probability nearly zero! Helmut 2012-06-16 17:08
        
        R-package randomizeBE d_labes 2012-07-06 09:54
        
        R-package randomizeBE Helmut 2012-07-06 12:51
  - randomization: validation ElMaestro 2012-06-16 13:31
    - randomization: runs test Helmut 2012-06-16 14:42
      - randomization: runs test ElMaestro 2012-06-16 14:48
        
        randomization: runs test Helmut 2012-06-16 15:10
      - very cool coding style ElMaestro 2012-06-16 19:12
        
        Better a good steal than a bad reinvention Helmut 2012-06-17 13:22
        
        Better a good steal than a bad reinvention ElMaestro 2012-06-17 19:58
        
        Sorry! Helmut 2012-06-18 13:26
        
        Sorry! ElMaestro 2012-06-18 15:19
        
        Dancing with the dice d_labes 2012-06-18 15:38
        
        Silly's randomization 2x2 xover d_labes 2012-06-18 16:30
        
        Silly's randomization 2x2 xover Helmut 2012-06-18 17:14
        
        Clumsy code Helmut 2012-06-18 17:42
        
        Clumsy code ElMaestro 2012-06-18 18:01
        
        Speed kills Helmut 2012-06-18 18:56
        
        Speed kills jag009 2012-09-17 21:46