Bioequivalence and Bioavailability Forum

Hi balakotu,

❝ how to construct 90% Confidence interval by using bootstrapping technique for bioequivalence assessment.

Assume the data has the distribution corresponding to what you see in your observed sample. Resample your sample a lot of times. Each times collect the measure you are interested in. Once all resamples have been gathered, derive the 90% CI.

If you use R then one place to start would be the 'boot' package. Search the web for examples. The package provides confidence interval options from user-defined models.
You can also program it up from scratch, but most people would probably rather have colon surgery done on them with a rusty scissor than do such a thing. Only a guess from my side.