Bioequivalence and Bioavailability Forum • Calculation

Calculation [Regulatives / Guidelines]

posted by sangeeta – India, 2011-11-29 19:30 (5327 d 05:08 ago) – Posting: # 7752
Views: 17,396

Hi Em,

❝ I think you have to do bootstrapping. So no averaging. Sample full data sets from the in vivo data listing 500 times with resampling and evaluate 500 times etc.

Thanks for your reply. Did you mean fitting model for individual subjects data?
But as per the guideline we should fit for mean of PD response for each dose.

Thanks,

Sangeeta.

Complete thread:

Orlistat Bioequivalence KR 2010-04-23 06:14
- To Abreviate or not to Abreviate d_labes 2010-04-23 09:28
  - What was really meant ElMaestro 2010-04-23 09:50
    - OGD Guidance Helmut 2010-04-23 12:42
  - To Abreviate or not to Abreviate KR 2010-04-23 15:01
    - Calm and serene d_labes 2010-04-23 15:47
    - To Abreviate or not to Abreviate ElMaestro 2010-04-24 08:16
      - To Abreviate or not to Abreviate KR 2010-04-26 06:03
        
        To Abreviate or not to Abreviate GSTATS 2010-05-27 18:30
        
        My lack of understanding ElMaestro 2010-05-28 00:54
        
        My lack of understanding GSTATS 2010-05-28 17:03
        
        My lack of understanding ElMaestro 2010-05-29 03:32
        
        My lack of understanding GSTATS 2010-05-29 05:28
        
        My lack of understanding KR 2010-05-31 08:51
        
        My lack of understanding ElMaestro 2010-06-01 16:13
        
        Calculation sangeeta 2011-11-29 17:58
        
        Calculation ElMaestro 2011-11-29 18:09
        
        Calculationsangeeta 2011-11-29 18:30
        
        Calculation ElMaestro 2011-11-30 11:35