Bioequivalence and Bioavailability Forum

Period DFs [Regulatives / Guidelines]

posted by d_labes  – Berlin, Germany, 2011-08-23 17:28 (5421 d 08:25 ago) – Posting: # 7296
Views: 8,754

Dear ElMaestro,

❝ I just wonder about another thing; in your original post that you link to above and this in this thread as well SAS says the model has 78 df's.

❝ Apprently (from your linked post)

❝ df periods = 2

❝ df seqs =1

❝ df subjs(seq) =75

❝ why df periods =2 and not 3?

Good question. Next question .

Seems there is some inter-dependence between periods and sequences.
Subjects with sequence TRTR have only periods 2 and 4, those with sequence RTRT have periods 1 and 3 (Note: we are dealing only with the data of the Reference).
Maybe this is the source of this odd degree of freedom?

BTW: If you have the data in R could you lm() them to see what's the result?

Complete thread:

• EMA replicate surprise d_labes 2011-08-23 13:01 
  • EMA replicate surprise ElMaestro 2011-08-23 13:15
    • Big bäng CV d_labes 2011-08-23 13:58
      • Big bäng CV ElMaestro 2011-08-23 15:02
        • Period DFsd_labes 2011-08-23 15:28
          • Period DFs Helmut 2011-08-23 15:36
          • Period DFs ElMaestro 2011-08-23 16:26
          • Period DFs ElMaestro 2011-08-23 16:58
            • Period DFs Helmut 2011-08-24 00:44
              • Lessons learned? d_labes 2011-08-24 11:24
                • Lessons learned? Helmut 2011-08-24 13:51
                • Lessons learned? ElMaestro 2011-08-28 21:34
            • Period DFs - EMA code literally in R d_labes 2011-08-24 10:47
              • Period DFs - EMA code literally in R ElMaestro 2011-08-24 13:04
                • call for expert’s opinions Helmut 2011-08-24 14:01
                  • call for expert’s opinions jdetlor 2011-11-01 03:05
                    • The finance sector ElMaestro 2011-11-02 09:48