Bioequivalence and Bioavailability Forum • link to the post of BEBAC golden collection

link to the post of BEBAC golden collection [Regulatives / Guidelines]

posted by durga09 – India, 2023-10-10 12:43 (580 d 08:58 ago) – Posting: # 23748
Views: 3,810

❝ I would point to the classical post (I'd say golden collection of this forum) provided by Detlew and Helmut here.

❝ It is 13 years old, but it is still the best. And the article mentioned there is 33 years old and also no one provided something better :-D )

Thank you AchievWin and mittyri.

Need a small help in the Output. In output I am getting Confidence intervals as

Hodges-Lehmann Estimation:

Type               90% Confidence Limits

Asymptotic (Moses)        -0.5000 1.5000

Exact                     -0.5000 1.5000

But as per guideline Tmax 90% CI should me 0.80 to 1.25 by this point does the study "pass" or "fail"

How can interpret the results?

Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5. Tabulators changed to spaces and BBcoded; see also this post #6. [Helmut]

Complete thread:

Tmax 90% confidence interval durga09 2023-09-08 10:21
- Tmax 90% confidence interval Achievwin 2023-09-09 12:44
  - link to the post of BEBAC golden collection mittyri 2023-09-10 19:55
    - link to the post of BEBAC golden collectiondurga09 2023-10-10 10:43
      - CI for difference in Tmax mittyri 2023-10-11 12:55
      - Tmax problems Helmut 2023-10-12 06:55