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Registerlong half-life and large variability [Regulatives / Guidelines]
Welcome to the home of funky and funny pharmacokinetics where "Garbage in Gospel out" is day of life.
1. allowing long washout periods have seen studies with 4 -5 months washout.
2. other choice we can imagine is Two stage adaptive study design and including ANCOA in place of ANOVA...
want to know what other experts think?
1. allowing long washout periods have seen studies with 4 -5 months washout.
2. other choice we can imagine is Two stage adaptive study design and including ANCOA in place of ANOVA...
want to know what other experts think?
❝ In short:
- pretty long half-life
- huge total variablity (i.e. within + between variability)
- total variability is expected to be explained to some degree by some covariates
Complete thread:
- long half-life and large variability martin 2020-07-29 16:57
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- long half-life and large variability ElMaestro 2020-07-29 21:24
- long half-life and large variability martin 2020-07-29 22:49
- long half-life and large variability ElMaestro 2020-07-30 08:17
- long half-life and large variability dshah 2020-08-10 06:18
- long half-life and large variability ElMaestro 2020-07-30 08:17
- long half-life and large variability martin 2020-07-29 22:49
- long half-life and large variabilityAchievwin 2020-08-12 15:22
- long half-life and large variability Helmut 2020-08-12 15:53
- long half-life and large variability ElMaestro 2020-07-29 21:24
Ing. Helmut Schütz