Bioequivalence and Bioavailability Forum

FDA BE: Truncate AUC for long half-life drug [Regulatives / Guidelines]

posted by d_labes  – Berlin, Germany, 2015-11-16 17:51 (3873 d 06:20 ago) – Posting: # 15642
Views: 3,265

Dear John!

Forgotten your own question on the same subject ? And Helmut's answer? Here is it.

Ok it's from 2012. But AFAIK there is no new information on this subject meanwhile. Beside the fact that for highly variable drugs truncation shouldn't be used. See f.i. this thread.

Complete thread:

• FDA BE: Truncate AUC for long half-life drug jag009 2015-11-16 16:28 
  • FDA BE: Truncate AUC for long half-life drugd_labes 2015-11-16 16:51