Bioequivalence and Bioavailability Forum

Update: S×F variance test [Regulatives / Guidelines]

posted by kumarnaidu – Mumbai, India, 2014-12-09 07:48 (4219 d 16:13 ago) – Posting: # 14031
Views: 16,983

Hello friends, I am getting below output using this SAS code. I dont know why I am getting value 0 (I think it is a rounded value) for FA(2,2).
Please guide me.

proc mixed data=sample method=reml ITDETAILS CL=WALD ALPHA=0.1;

class Subject sequence period formulation;

model logDATA=sequence period formulation/ddfm=satterth; 

random formulation/type=FA0(2) subject=subject G; 

repeated/group=formulation subject=subject; 

lsmeans formulation/pdiff cl alpha=0.1; 

estimate 'T-R' formulation 1 -1 /CL ALPHA=0.1; 

ods output Estimates=BLUEUN CovParms=COVUN AsyCov=ascovun; 

run;

Dependent  Parameter                   Estimate

Ln(data)   FA(1,1)                     0.8530

Ln(data)   FA(1,2)                     0.8284

Ln(data)   FA(2,2)                     0

Ln(data)   Res(Formulation R*Subject)  0.2021

Ln(data)   Res(Formulation T*Subject)  0.1174

—
Kumar Naidu

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Update: S×F vari­­ance test [Regulatives / Guidelines]

Complete thread:

Update: S×F variance test [Regulatives / Guidelines]