ODT vs. IR [Regulatives / Guidelines]

posted by Dr_Dan  – Germany, 2014-03-17 11:30 (4485 d 22:20 ago) – Posting: # 12635
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Dear fno
If taking ODT with water results in a biovailability decreased by 30% compared to taking ODT without water then this would imply that a high portion of bioavailability (i.e. 30%) is caused by absorption within the oral cavity. In this case it would be highly unlikely that ODT without water and IR with water have the same bioavailability.
Kind regards
Dr_Dan

Kind regards and have a nice day
Dr_Dan

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