Bioequivalence and Bioavailability Forum • Sequence Effect on Endogenous Drugs

Sequence Effect on Endogenous Drugs [Regulatives / Guidelines]

posted by jag009 – NJ, 2014-02-11 18:21 (4516 d 14:23 ago) – Posting: # 12401
Views: 10,494

Hi,

❝ Pass with the same significant effects (only sequence effect for both analysis). P-value was 3.41% for Cmax and 6.92% for AUC0-72 in the non-corrected analysis and 8.84% for Cmax and 14.7% for AUC0-72.

Just to clarify (brain cramp this morning...)

You meant:
Non-corrected Analysis p values: Cmax = 0.0341, AUC 0.0692
Corrected Analysis p values: Cmax = 0.0884, AUC 0.1470

These are p values for sequence effect? If not, what are they?

John

Complete thread:

Sequence Effect on Endogenous Drugs Lucas 2014-02-10 20:01
- Sequence Effect on Endogenous Drugs ElMaestro 2014-02-10 20:09
  - Sequence Effect on Endogenous Drugs Lucas 2014-02-11 12:24
    - Sequence Effect on Endogenous Drugs ElMaestro 2014-02-11 13:26
      - Sequence Effect on Endogenous Drugs Lucas 2014-02-11 17:38
- Sequence Effect on Endogenous Drugs jag009 2014-02-10 21:35
  - Sequence Effect on Endogenous Drugs Lucas 2014-02-11 12:28
    - Sequence Effect on Endogenous Drugsjag009 2014-02-11 17:21
      - Sequence Effect on Endogenous Drugs Lucas 2014-02-11 17:33
- Sequence Effect on Endogenous Drugs Helmut 2014-02-11 15:07
  - Curious jag009 2014-02-11 17:16
  - Sequence Effect on Endogenous Drugs Lucas 2014-02-11 17:45
- Four studies with the same formulation Lucas 2014-02-11 17:32
  - Four studies with the same formulation jag009 2014-02-11 20:01