Bioequivalence and Bioavailability Forum • calculation of Washout period

calculation of Washout period [Regulatives / Guidelines]

posted by drgunasakaran1 – 2014-01-17 18:59 (4548 d 01:35 ago) – Posting: # 12191
Views: 24,147

Dear Mr Mahesh,

❝ EMA recommended 10 times t 1/2.

As per EMA BE Guidance "Normally at least 5 elimination half-lives should be provided as Wash out period"
Canadian Guidance states that washout period should be not less than 10 times the mean terminal half-life of the drug.

—
Dr Gunasakaran Sambandan MD
Disclaimer: The replies/posts are my personal opinions, and they do not represent my company's views on the same. LinkedIn

Complete thread:

calculation of Washout period bharathnadh.pharma 2014-01-17 09:48
- calculation of Washout period Dr_Dan 2014-01-17 11:48
  - calculation of Washout period Mahesh M 2014-01-17 12:26
    - calculation of Washout period jag009 2014-01-17 17:41
    - calculation of Washout perioddrgunasakaran1 2014-01-17 17:59
      - calculation of Washout period Mahesh M 2014-01-20 10:46
      - calculation of Washout period rezowan 2014-01-23 19:13
        
        Theoretical carry-over Helmut 2014-01-23 19:57
        
        Theoretical carry-over bharathnadh.pharma 2014-01-25 17:33
  - calculation of Washout period bharathnadh.pharma 2014-01-18 09:45
    - calculation of Washout period drgunasakaran1 2014-01-18 15:37
      - calculation of Washout period bharathnadh.pharma 2014-01-20 05:44
        
        calculation of Washout period Ohlbe 2014-01-20 06:37