PE consideration [Regulatives / Guidelines]

posted by Jay – India, 2013-09-11 13:02 (4673 d 11:42 ago) – Posting: # 11474
Views: 8,808

Dear Helmut,

Can we consider CV from a range, i.e. we got 24.7 CV from pilot and literature reports as high as 30. So can we use Cv of 26 or 27 for sample size calculation?

And also we got point estimate of 1.06. So can we use 1.06 PE in our sample size calculation. Can we also use PE from literature, we observed PE of 1.08. Or we have to stick to 0.95 to 1.05%?

Complete thread:

UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,570 registered users;
294 visitors (0 registered, 294 guests [including 25 identified bots]).
Forum time: 00:45 CEST (Europe/Vienna)

The real struggle is not between the right and the left
but between the party of the thoughtful
and the party of the jerks.    Jimmy Wales

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5