CL of CV [Regulatives / Guidelines]

posted by Jay – India, 2013-09-06 17:21 (4676 d 04:52 ago) – Posting: # 11452
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Thanks Helmut.

Is this method i.e. Upper CI of CV, should be considered while calculating sample size everytime? We use highest CV of Cmax, Auc0-t or AUCinf observed in pilot or from any literature.

And is this use of upper CI of CV in sample size calculation commonly used in BE Studies? As much unawareness about its usage in Sample size calculation is not here.

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