Bioequivalence and Bioavailability Forum

Narrow Therapeutic statistics [Regulatives / Guidelines]

posted by kumarnaidu – Mumbai, India, 2013-04-10 12:27 (4830 d 07:26 ago) – Posting: # 10391
Views: 4,795

Power calculation in sas for NTI drug
Hello everybody, for calculating power in bio equivalence we use following code in SAS. Can anybody tell me what is 1.25 in 3rd line. Is it upper limit of ratio (0.8 to 1.25). If it is upper limit then in that case should I replace it by 1.11 for analysis of NTI drug. Please reply.....

pt=tinv(0.05,df,0);

apt=abs(pt);

pw=(log(1.25)/se-apt);

Power=100*probt(pw,df);

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Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]

Complete thread:

• Narrow Therapeutic statistics Compliance 2012-07-09 07:13 
  • Narrow Therapeutic statistics hiren379 2012-07-11 06:17
    • Narrow Therapeutic statistics Compliance 2012-07-11 06:29
      • Narrow Therapeutic statistics hiren379 2012-07-11 08:59
    • Tmax required for the FDA? Helmut 2012-07-11 15:59
  • Narrow Therapeutic statisticskumarnaidu 2013-04-10 10:27
    • Power? d_labes 2013-04-10 10:38
  • Narrow Therapeutic statistics kvgreddy06 2014-09-01 17:13
    • Narrow Therapeutic statistics Compliance 2014-09-10 12:07