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RegisterEnterohepatic recirculation [Study Assessment]
Hi Chirage,
Not surprise. Some studies of mine had > 60% of the subject with Tmax > 14 hrs while others had like 1 or 2 subjects.
You mean AUCinfinity? For subjects who exhibit the late Tmax, do they show a peak at (e.g.) Tmax > 14 hours for both treatments?
John
❝ carried out a pilot study and there was no such observation.
Not surprise. Some studies of mine had > 60% of the subject with Tmax > 14 hrs while others had like 1 or 2 subjects.
❝ The last sample is at 72hrs, the observation of double absorption is seen from 16th hour onwards (Cmax) and in some cases 24hrs also (Cmax) and therefore AUC estimates are not reliable
You mean AUCinfinity? For subjects who exhibit the late Tmax, do they show a peak at (e.g.) Tmax > 14 hours for both treatments?
John
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Ing. Helmut Schütz