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RegisterTo calculate AUC0-inf in Scaled average bioequivalence [Study Assessment]
Dear All,
Our study is a partial reference replicate. The sequence here is TRR, RTR and RRT.
After estimating the PK parameters, there are certain subjects which don't have their Rsq values greater than 80%. So these are subjects are not used for the statiscal calculation of AUC0-inf. Since we are removing subjects which are less than 80%, one entire sequence (RRT) is not available. While we are analyzing in SAS, we are getting an error "Average is not estimable".
We want to know whether this error is occuring because of the missing sequence.
Edit: Category changed. [Helmut]
Our study is a partial reference replicate. The sequence here is TRR, RTR and RRT.
After estimating the PK parameters, there are certain subjects which don't have their Rsq values greater than 80%. So these are subjects are not used for the statiscal calculation of AUC0-inf. Since we are removing subjects which are less than 80%, one entire sequence (RRT) is not available. While we are analyzing in SAS, we are getting an error "Average is not estimable".
We want to know whether this error is occuring because of the missing sequence.
Edit: Category changed. [Helmut]
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Regards,
Nee…
Regards,
Nee…
Complete thread:
- To calculate AUC0-inf in Scaled average bioequivalenceaquapurple 2012-08-24 11:50
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Completely lost sequence in partial replicate Helmut 2012-08-24 20:07
Ing. Helmut Schütz