Bioequivalence and Bioavailability Forum

Missing samples in terminal elimination phase [Study As­sess­ment]

posted by Jaime_R – Barcelona, 2009-10-13 20:24 (6100 d 16:47 ago) – Posting: # 4349
Views: 8,286

Dear Yung-jin!

❝ ❝ Why didn't you use a truncated AUC₇₂ approach?

❝ Since the study has been done, was it too late to switch to truncated AUC

❝ method?

Oh yes, sure. I should have added a to my rhetorical question...

❝ ❝ You have some options [...]

❝ These are very nice suggestions [...] should be carefully considered

❝ when developing a BE study protocol.

Maybe. But I would put all efforts not running into such a situation, i.e. avoid sampling for one month.

Complete thread:

• Missing samples in terminal elimination phase Bhupesh 2009-10-12 14:14 
  • Missing samples in terminal elimination phase Jaime_R 2009-10-12 14:51
    • Missing samples in terminal elimination phase yjlee168 2009-10-12 22:53
      • Missing samples in terminal elimination phaseJaime_R 2009-10-13 18:24
  • Missing samples in terminal elimination phase Helmut 2009-10-12 15:18