Comparing two plasma concentration profiles [Study As­sess­ment]

posted by Darborn – Taiwan, 2025-10-17 07:40 (250 d 22:21 ago) – Posting: # 24464
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Hi everyone

I was reading the lecture slides presenting by Helmut in SAAMnow called "Data Manipulation in Bio­equi­va­lence". At the page 8, it said comparing plasma concentration profiles with f2 method. I tried with some profiles but got negative f2 values, so does the data need to be transformed or normalized? Anyone has ideas?

Thanks

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