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RegisterHow to understand what is guilty? [Study Assessment]
I usually look at the individual test to reference ratios. They can be very informative regarding the variability of the study drug and to understand what has gone wrong. For instance, if almost all your TR ratios fall below 1 that may indicate that the test drug absorption is in fact lower than the reference product; on the other side, if they're equally distributed above and below 1 - even if some of the ratios are "outliers" - you have a strong evidence of a study really underpowered and possibly an highly variable drug. Post-hoc power calculations may also be useful. In my opinion, using this data is more informative than looking at the CI alone.
Complete thread:
- How to understand what is guilty? BE-proff 2016-07-30 18:21
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- How to understand what is guilty? ElMaestro 2016-07-30 23:15
- How to understand what is guilty? BE-proff 2016-08-02 17:06
- How to understand what is guilty?DavidManteigas 2016-08-08 11:18
- Post-hoc power is useless! d_labes 2016-08-09 08:31
- Post-hoc power is useless! ElMaestro 2016-08-09 13:00
- Post-hoc power is useless! d_labes 2016-08-09 14:30
- Post-hoc power is useless! ElMaestro 2016-08-09 16:17
- Post-hoc power is useless! d_labes 2016-08-09 14:30
- Post-hoc power is useless! DavidManteigas 2016-08-09 13:51
- Post-hoc power is useless! d_labes 2016-08-09 14:11
- Post-hoc power is useless! ElMaestro 2016-08-09 13:00
- Post-hoc power is useless! d_labes 2016-08-09 08:31
- How to understand what is guilty? ElMaestro 2016-07-30 23:15
Ing. Helmut Schütz