Bioequivalence and Bioavailability Forum

CV from CI [Study Assessment]

posted by Helmut – Vienna, Austria, 2013-11-19 17:42 (4191 d 16:45 ago) – Posting: # 11916
Views: 10,360

Hi ElMaestro,

❝ I get a 26% CV for AUC, which is a bit higher than the observed CV for Cmax.

Which number-cruncher are you using? Mighty PowerTOST gives 23.9% for AUC and 20.4% for C_max. Try:

library(PowerTOST)

round(100*CVfromCI(lower=0.83186, upper=1.0402,  n=26, design="2x2"), 1)

round(100*CVfromCI(lower=0.61796, upper=0.74855, n=26, design="2x2"), 1)

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Helmut Schütz

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Complete thread:

Failed Fed study on Indapamide MR Clarc 2013-11-19 11:04
- Failed Fed study on Indapamide MR Dr_Dan 2013-11-19 14:31
- Failed Fed study on Indapamide MR ElMaestro 2013-11-19 15:56
  - CV from CIHelmut 2013-11-19 16:42
    - CV from CI ElMaestro 2013-11-19 16:59
      - Misprint gremlin Helmut 2013-11-19 17:05
  - Failed Fed study on Indapamide MR Clarc 2013-11-20 07:28
- Failed Fed study on Indapamide MR jag009 2013-11-19 19:45
  - Failed Fed study on Indapamide MR Clarc 2013-11-20 07:36
    - Failed Fed study on Indapamide MR luvblooms 2013-11-20 08:51
      - Failed Fed study on Indapamide MR Clarc 2013-11-20 10:59
        
        Failed Fed study on Indapamide MR jag009 2013-11-20 17:30
        Failed Fed study on Indapamide MR luvblooms 2013-11-21 06:00
        
        Failed Fed study on Indapamide MR Clarc 2013-11-21 07:11

CV from CI [Study As­sess­ment]

Complete thread:

CV from CI [Study Assessment]