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Registertruncated AUC [NCA / SHAM]
Dear Helmut,
Articles and Guidances have said that the use of truncated area under the curve could be a significant advantage for BE studies of drugs with long half-lives and low intrasubject variability. So, I would like to know why is not truncated AUC a good option to high intrasubject variability drug?
Regards,
Daniel Rossi de Campos
Brazil
Articles and Guidances have said that the use of truncated area under the curve could be a significant advantage for BE studies of drugs with long half-lives and low intrasubject variability. So, I would like to know why is not truncated AUC a good option to high intrasubject variability drug?
Regards,
Daniel Rossi de Campos
Brazil
Complete thread:
- truncated AUCdrcampos 2007-07-25 17:21
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- truncated AUC Helmut 2007-07-25 17:39
Ing. Helmut Schütz