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RegisterCmin calculation steady state [NCA / SHAM]
Dear RVR
Thanks a lot for the responses.
In a case for multiple dosing steady state study for one of the MR formulations with a dosing interval of 24 hours and the pre-dose samples were collected for 7 days and serial sampling till 24 hours on the 7 day.
Which all time points will be used for Cmin calculation.
How should we calculate the Ka (absorption constant here) to be used in the formula for Cmin calculation
Regards
VG
Thanks a lot for the responses.
In a case for multiple dosing steady state study for one of the MR formulations with a dosing interval of 24 hours and the pre-dose samples were collected for 7 days and serial sampling till 24 hours on the 7 day.
Which all time points will be used for Cmin calculation.
How should we calculate the Ka (absorption constant here) to be used in the formula for Cmin calculation
Regards
VG
Complete thread:
- Cmin calculation steady state VG 2012-07-30 07:02
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Cmin calculation steady state RVR 2012-07-30 11:51
- Cmin calculation steady stateVG 2012-07-31 11:14
- Cmin - search, search, search and once more: search d_labes 2012-07-31 13:33
- Cmin calculation steady state RVR 2012-07-30 11:51
Ing. Helmut Schütz