Bioequivalence and Bioavailability Forum

What does ‘max’ in Cmax mean? [NCA / SHAM]

posted by Helmut  – Vienna, Austria, 2023-06-27 15:44 (588 d 23:11 ago) – Posting: # 23625
Views: 2,865

Hi Imph,

❝ ❝ Cmax is defined as highest concentration obtained after dose irrespective of number of peaks. The peaks can be observed due to various reason like enterohepatic recirculation and many more.

❝

❝ […] So I have to choose the peak showing the highest concentration among the two?

Read what Divyen stated above again. By definiton the highest concentration!

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

• concentration-time profile with two peaks or more Imph 2023-06-27 13:06 
  • concentration-time profile with two peaks or more dshah 2023-06-27 13:13
    • concentration-time profile with two peaks or more Imph 2023-06-27 13:26
      • What does ‘max’ in Cmax mean?Helmut 2023-06-27 13:44
        • What does ‘max’ in Cmax mean? Imph 2023-06-27 15:18
          • Which software? Helmut 2023-06-27 15:24
            • Which software? Imph 2023-06-27 16:56
              • tmax ≠ Cmax 🙂 Helmut 2023-06-27 17:03
                • tmax ≠ Cmax 🙂 Imph 2023-06-27 17:33
                  • tmax ≠ Cmax 🙂 BEQool 2023-06-27 18:25