t1/2 prior to Tmax in BE study [NCA / SHAM]

posted by Dhruv Shah – India, 2016-03-11 04:48 (3385 d 16:23 ago) – Posting: # 16088
Views: 7,092

In a recent BE study I observed that t1/2 (1 hrs) was faster than Tmax (1.3 hrs). I wanted to know that what does it mean? Moreover if we analyze the data of individual subjects, the occurrence was more in test as compared to reference product. Do we need any special design precautions in such study?

Edit: Category changed. Please follow the Forum’s Policy. [Helmut]

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,674 registered users;
25 visitors (0 registered, 25 guests [including 18 identified bots]).
Forum time: 22:11 CEST (Europe/Vienna)

In matters of style, swim with the current;
in matters of principle, stand like a rock.    Thomas Jefferson

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5