G (Kinetica) = R²adj (WinNonlin) [NCA / SHAM]

posted by Helmut Homepage – Vienna, Austria, 2008-02-04 02:12 (6345 d 06:32 ago) – Posting: # 1576
Views: 30,025

Dear Ohlbe!

❝ … strange enough there’s a parameter ‘G’ in the output, which is neither described in the online-help nor the manual (v4.1.1, 2007).

❝ I will try to find out the next days, what this parameter might be…


OK, I ran the example in Kinetica; the parameter ‘G’ in the output is numerically identical to R2adj.

Just another quote supporting “eye-ball PK”:*

‘The selection of the most suitable time interval cannot be left to a programmed algorithm based on mathematical criteria, but necessitates scientific judgment by both the clinical pharmacokineticist and the person who determinend the concentrations and knows about their reliability.’




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