Bioequivalence and Bioavailability Forum • Methods for calculation of half lives

Methods for calculation of half lives [NCA / SHAM]

posted by Ohlbe – France, 2008-02-03 00:00 (6346 d 05:17 ago) – Posting: # 1574
Views: 29,466

Dear HS,

❝ Personally I'm sticking to 'eyeball-PK' in this respect. The standard textbook specialized in regression emphasizes the importance of visual inspection of the fit.^[1] Other rather old, but still valid references are given below.^[2,3]

Yes, I agree ! And I'm also not convinced by R².

What about Akaike's criterion ? I think Kinetica uses it, right ?

Regards
Ohlbe

Complete thread:

Methods for calculation of half lives d_labes 2008-02-01 14:58
- Methods for calculation of half lives Helmut 2008-02-01 16:59
  - Methods for calculation of half livesOhlbe 2008-02-02 23:00
    - Minimum AIC?! Helmut 2008-02-03 13:49
      - G (Kinetica) = R²adj (WinNonlin) Helmut 2008-02-04 01:12
  - Methods for calculation of half lives d_labes 2008-02-04 16:43
    - MAIC and beyond... Helmut 2008-02-04 17:49
- TTT method Helmut 2008-05-10 13:56
  - TTT method d_labes 2008-05-16 09:12
    - TTT method Helmut 2008-05-16 17:21
      - TTT method d_labes 2008-05-23 15:43
        
        TTT method hiren379 2012-07-11 11:11
        
        TTT method Ohlbe 2012-07-11 11:37
        
        TTT method hiren379 2012-07-11 11:44
        
        TTT method Ohlbe 2012-07-11 12:16
        
        TTT method hiren379 2012-07-11 12:53
        
        Eyeball-PK Helmut 2012-07-11 14:37
        
        Eyeball-PK hiren379 2012-07-11 15:28
        
        Eyeball-PK Helmut 2012-07-11 15:47
        
        Eyeball-PK hiren379 2012-07-11 16:24