Bioequivalence and Bioavailability Forum • BE with 1 not included in CI ?

BE with 1 not included in CI ? [RSABE / ABEL]

posted by Coja66 – 2013-01-16 11:12 (4501 d 09:45 ago) – Posting: # 9862
Views: 6,908

Hi all,

For a client, I am performing the PK for a BE study using acceptance ranges of 0.50-2.00 (which are way to wide for my preference by the way). Now the results show that 90% CI are included in these ranges, but the 1 is not included the CI. I know this is not relevant for assessing BE, but for some reason worries me, especially since the acceptance ranges are so wide. Is there indeed a reason to worry, or not ?

Thanks for the input !
Coja

Complete thread:

BE with 1 not included in CI ?Coja66 2013-01-16 10:12
- BE with 1 not included in CI ? ElMaestro 2013-01-16 11:38
  - BE with 1 not included in CI -danish twist d_labes 2013-01-16 15:07
    - BE with 1 not included in CI -danish twist ElMaestro 2013-01-16 17:46
      - BE with 1 not included in CI -danish twist The Outlaw Torn 2013-01-17 13:27
    - BE with 1 not included in CI -danish twist bjkim97 2013-02-06 05:56
      - EMA widenend ABEL d_labes 2013-02-06 09:27