Partial (RSABE) vs Full replicate [RSABE / ABEL]
Dear Luv,
Good Morning
Both designs are appropriate to be used for Reference scaling. But full replicate design has one extra arm (period) as "T" which is not required in reference scaling while in partial replicate design, (if you are new to this design) statistical calculations are bit complex.
I will suggest you to go with partial replicate.
Regards,
GSTATS
Good Morning
❝ For a molecule showing Intra-subject variability of 40-50% in Cmax and 33% in AUC, which study design will be more appropriate, Partial replicate(RTR---RSABE) or Full replicate (RTRT)?
Both designs are appropriate to be used for Reference scaling. But full replicate design has one extra arm (period) as "T" which is not required in reference scaling while in partial replicate design, (if you are new to this design) statistical calculations are bit complex.
I will suggest you to go with partial replicate.
Regards,
GSTATS
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Let Noble Thoughts come from Every Side: RIG VEDA
Let Noble Thoughts come from Every Side: RIG VEDA
Complete thread:
- Partial (RSABE) vs Full replicate luvblooms 2011-06-14 06:19
- Partial (RSABE) vs Full replicateGSTATS 2011-06-14 06:53
- Partial (RSABE) vs Full replicate Dr_Dan 2011-06-14 08:49
- Partial (RSABE) vs Full replicate luvblooms 2011-06-14 09:07
- Partial (RSABE) vs Full replicate Dr_Dan 2011-06-14 08:49
- Partial (RSABE) vs Full replicate rajneesh singh 2011-06-14 13:47
- Partial (RSABE) vs Full replicateGSTATS 2011-06-14 06:53