Bioequivalence and Bioavailability Forum

Partial (RSABE) vs Full replicate [RSABE / ABEL]

posted by luvblooms  – India, 2011-06-14 08:19 (5496 d 18:19 ago) – Posting: # 7117
Views: 9,008

Dear All

Good morning

For a molecule showing Intra-subject variability of 40-50% in Cmax and 33% in AUC, which study design will be more appropriate, Partial replicate(RTR---RSABE) or Full replicate (RTRT)?

Thanks

Luv

Complete thread:

• Partial (RSABE) vs Full replicateluvblooms 2011-06-14 06:19 
  • Partial (RSABE) vs Full replicate GSTATS 2011-06-14 06:53
    • Partial (RSABE) vs Full replicate Dr_Dan 2011-06-14 08:49
      • Partial (RSABE) vs Full replicate luvblooms 2011-06-14 09:07
  • Partial (RSABE) vs Full replicate rajneesh singh 2011-06-14 13:47