Partial (RSABE) vs Full replicate [RSABE / ABEL]

posted by luvblooms  – India, 2011-06-14 08:19 (5494 d 15:46 ago) – Posting: # 7117
Views: 8,997

Dear All

Good morning :flower:

For a molecule showing Intra-subject variability of 40-50% in Cmax and 33% in AUC, which study design will be more appropriate, Partial replicate(RTR---RSABE) or Full replicate (RTRT)?

Thanks

Luv
—
~A happy Soul~

Complete thread:

UA Flag
Activity
 Admin contact
23,656 posts in 4,994 threads, 1,570 registered users;
265 visitors (0 registered, 265 guests [including 27 identified bots]).
Forum time: 00:06 CEST (Europe/Vienna)

Most scientists today are devoid of ideas, full of fear, intent on
producing some paltry result so that they can add to the flood
of inane papers that now constitutes “scientific progress”
in many areas.    Paul Feyerabend

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5