Bioequivalence and Bioavailability Forum

Replicate design AGAIN [RSABE / ABEL]

posted by Dr Andrew Leary – Ireland, 2011-04-27 14:21 (5132 d 03:17 ago) – Posting: # 6946
Views: 9,073

Dear El Maestro

❝ If I understand your post correctly, your worry seems to be whether patient X is in sequence RR or in sequence RR . Sequence, however, is a between-factor. Try and run the standard model without sequence as a factor on your ref data. And try for comparison to run a normal 2-period study without Sequence as a factor.

My data manager tells me that SAS will not allow sequence to be dropped from the regression (mixed effects?) model.

We've thus fallen at the first hurdle...

Any other ideas?

Regards

Andrew

Complete thread:

• Replicate design Dr Andrew Leary 2011-04-21 11:50 
  • Replicate design ElMaestro 2011-04-21 13:04
    • Replicate design Dr Andrew Leary 2011-04-21 21:53
    • Replicate design AGAINDr Andrew Leary 2011-04-27 12:21
      • Replicate design limbo Helmut 2011-04-27 13:43
        • Replicate design limbo Dr Andrew Leary 2011-04-27 16:11
          • Replicate design limbo Helmut 2011-04-27 16:52
            • Replicate design Vienna waltz d_labes 2011-04-28 08:54
              • Replicate design EMA Morris dance Helmut 2011-04-28 14:17
                • EMA Morris dance d_labes 2011-05-02 12:55