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RegisterMixed MoM [RSABE / ABEL]
Dear EM,
Thanx for the flowers.
That was also my opinion before. But what I liked to illustrate with my post is that this is not always true. We have here no missing values, balance also. But very different results of the first part of the scaled average BE criterion.
BTW: I'm not sure if MoM is a misnomer. But in the FDA guidance the analogous evaluation if the IBE and PBE criterion via sample statistics is named such.
BTW2: I'm not sure where the bear dataset comes from and if the described phenomenon is real or relies on an artificial dataset.
❝ Nice post d_labes,
Thanx for the flowers.
❝ Last, to address my own bonus question partially, I think there could be a practical difference between the FDA approach and the way by a Mixed Model. They may achieve exactly the same in the cases where there are no missing values.
That was also my opinion before. But what I liked to illustrate with my post is that this is not always true. We have here no missing values, balance also. But very different results of the first part of the scaled average BE criterion.
BTW: I'm not sure if MoM is a misnomer. But in the FDA guidance the analogous evaluation if the IBE and PBE criterion via sample statistics is named such.
BTW2: I'm not sure where the bear dataset comes from and if the described phenomenon is real or relies on an artificial dataset.
—
Regards,
Detlew
Regards,
Detlew
Complete thread:
- Reference scaled BE - FDA (and FARTSSIE update) ddubins 2010-04-26 20:28
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Reference scaled ABE - FDA d_labes 2010-04-27 08:58
- Reference scaled ABE - FDA ElMaestro 2010-04-27 13:39
- Factor 2 is unbiased d_labes 2010-04-27 14:30
- Biased bonus from MoM d_labes 2010-05-04 12:10
- Biased bonus from MoM ElMaestro 2010-05-04 12:54
- Mixed MoMd_labes 2010-05-04 14:40
- Mixed MoM ElMaestro 2010-05-04 15:08
- R and G, CSH and UN d_labes 2010-05-05 10:42
- A sailor gets confused ElMaestro 2010-05-05 11:49
- Confused V/Z matratzen and tips d_labes 2010-05-05 14:49
- superb post! ElMaestro 2010-05-05 21:32
- Gambling with UN d_labes 2010-05-06 11:00
- superb post! ElMaestro 2010-05-05 21:32
- Confused V/Z matratzen and tips d_labes 2010-05-05 14:49
- A sailor gets confused ElMaestro 2010-05-05 11:49
- R and G, CSH and UN d_labes 2010-05-05 10:42
- Mixed MoM yjlee168 2010-05-05 09:12
- Mixed MoM ElMaestro 2010-05-04 15:08
- Mixed MoMd_labes 2010-05-04 14:40
- Biased bonus from MoM ElMaestro 2010-05-04 12:54
- Reference scaled ABE - FDA ElMaestro 2010-04-27 13:39
- Reference scaled BE - FDA (and FARTSSIE update) KR 2010-04-27 13:14
- Reference scaled BE - EMA Helmut 2010-04-27 14:58
- Reference scaled BE - EMA ddubins 2010-04-27 17:52
- Partial replicate design and FDA ABE code d_labes 2010-04-28 09:47
- Reference scaled BE - EMA Helmut 2010-04-28 14:46
- Switching - null sWR d_labes 2010-05-04 14:04
- Reference scaled BE - EMA ddubins 2010-04-27 17:52
- The unknown x d_labes 2010-05-06 13:26
- The unknown x jdetlor 2010-09-28 17:22
- Unknown x corrected? d_labes 2010-10-01 12:14
- Unknown x corrected? Qilex 2016-09-21 12:25
- Official unknown x d_labes 2016-09-21 13:22
- Unknown x corrected? Qilex 2016-09-21 12:25
- Unknown x corrected? d_labes 2010-10-01 12:14
- The unknown x jdetlor 2010-09-28 17:22
- Reference scaled ABE - FDA d_labes 2010-04-27 08:58
Ing. Helmut Schütz