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RegisterIf we have any methods to widen CI in parallel design with high variance drug? [RSABE / ABEL]
Dear all,
Recently I meet a problem about sample size of high variance drug, normally, we will design a repeated cross-over trial for this kind of drug. But this time it is designed as a parallel study due to some reasons. But the sample size is too much based on 80%-125% BE CI. So my quesion is if we have any method to widen the CI like RSABE in cross-over study? Thank you very mcuh.
Sincerely,
libaiyi
Recently I meet a problem about sample size of high variance drug, normally, we will design a repeated cross-over trial for this kind of drug. But this time it is designed as a parallel study due to some reasons. But the sample size is too much based on 80%-125% BE CI. So my quesion is if we have any method to widen the CI like RSABE in cross-over study? Thank you very mcuh.
Sincerely,
libaiyi
Complete thread:
- If we have any methods to widen CI in parallel design with high variance drug?libaiyi 2021-02-02 09:39
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- If we have any methods to widen CI in parallel design with high variance drug? ElMaestro 2021-02-02 11:12
- If we have any methods to widen CI in parallel design with high variance drug? libaiyi 2021-02-02 11:40
- If we have any methods to widen CI in parallel design with high variance drug? ElMaestro 2021-02-02 11:12
Ing. Helmut Schütz