Bioequivalence and Bioavailability Forum • CI equation for 4 Period, 2 sequences "Full Replicate"

CI equation for 4 Period, 2 sequences "Full Replicate" [RSABE / ABEL]

posted by Mohamed Yehia – Egypt, 2017-10-29 18:00 (3161 d 11:30 ago) – Posting: # 17941
Views: 6,335

Dear All,

I want to know the equation used to calculate the CI for 4 period, 2 sequences BE study using sequences:

Seq1: TRTR
Seq2: RTRT

According to my knowledge the Degree of Freedom used in the equation is (n1+n2)-2. However, I am afraid that the DF shall be 3n-4. So, which one shall I use

Thanks.

Complete thread:

CI equation for 4 Period, 2 sequences "Full Replicate"Mohamed Yehia 2017-10-29 17:00
- DF for 4 Period, 2 sequences "Full Replicate" Helmut 2017-10-29 19:02
  - DF for 4 Period, 2 sequences "Full Replicate" Mohamed Yehia 2017-10-29 19:50