Bioequivalence and Bioavailability Forum • TRT / RTR Design

TRT / RTR Design [RSABE / ABEL]

posted by Yura – Belarus, 2017-05-01 11:34 (2934 d 12:58 ago) – Posting: # 17285
Views: 11,196

Dear All
Do I understand correctly that using the TRT / RTR design it will be necessary to compare the RR and TT extension interval that are built on the data of subjects of different groups (50% of study subjects are used for RR and 50% of other subjects for TT), the comparison will be for different Subjects? Or will it be necessary to compare the extension interval R-R, built on 50% of the subjects, and the confidence interval T-R, built on the data of all subjects?
The appropriate sample size must be.
Alpha correction.
Best regards

Complete thread:

TRT / RTR DesignYura 2017-05-01 09:34
- TRT / RTR Design mittyri 2017-05-02 18:38
  - TRT / RTR Design Yura 2017-05-02 21:19
    - TRT / RTR Design Helmut 2017-05-02 22:04
      - TRT / RTR Design Yura 2017-05-03 07:41
        
        TRT / RTR Design Helmut 2017-05-03 21:49
        
        TRT / RTR Design ElMaestro 2017-05-03 22:04
        
        TRT / RTR Design Helmut 2017-05-06 18:33
        
        TRR / RTT Design Yura 2017-05-09 11:35
        
        TRR / RTT Design Helmut 2017-05-09 13:06
        
        TRR / RTT Design Yura 2017-05-09 16:18
        
        TRR / RTT Design Helmut 2017-05-09 16:56
        
        TRR / RTT Design Yura 2017-05-09 17:36
        
        TRR / RTT Design Helmut 2017-05-09 17:53
        
        TRR / RTT Design Yura 2017-05-09 18:07