Constraints, algebra, jommetry and such [RSABE / ABEL]

posted by ElMaestro  – Denmark, 2015-03-31 16:26 (4108 d 12:27 ago) – Posting: # 14641
Views: 30,752

Hi Yung-jin,

❝ ❝ This is why the lm, PROC GLM, lmer etc take the appropriate decision for you. These functions or procedures will exclude the subjects that need to be excluded...


Upon furter reflexion: I might actually be wrong about a mixed model taking care to expell subjects that do not have one T and one R at least. Probably it can be said the whole point of the mixe models is they don't and this is the direct reason why a subject with a missing period in 222BE study will still count towards the result if it is for some reason fit by a mixed model and subject as random. I need to sit down and work the general model constraints to know for sure.
This quickly gets into a territory where I don't have the skills. Try and google "likelihood of a matrix" :crying:

Pass or fail!
ElMaestro

Complete thread:

UA Flag
Activity
 Admin contact
23,656 posts in 4,994 threads, 1,570 registered users;
161 visitors (0 registered, 161 guests [including 43 identified bots]).
Forum time: 04:54 CEST (Europe/Vienna)

It requires a very unusual mind
to undertake the analysis of the obvious.    Alfred North Whitehead

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5