Bioequivalence and Bioavailability Forum

Noise debugged [RSABE / ABEL]

posted by d_labes  – Berlin, Germany, 2014-07-24 15:47 (3946 d 22:15 ago) – Posting: # 13307
Views: 12,839

Dear Helmut,

❝ ❝ Where does the tremendous noise in your pictures came from?

❝

❝ Quick and dirty as ever...

Mea culpa, mea maxima culpa.
Quick and dirty was on my side. The noise comes from a nasty bug in power.2stage.GS() which let the power values jumping around and not converging with increasing number of sims .
I noted some of this behaviour already earlier and thus called this function "experimental". But than forgot it.

Corrected version is under way. Sorry for any inconvenience.

BTW: To calculate without futility criterion set fCrit="PE" and set fClower=0 (implies fCupper=Inf).

Complete thread:

• EMA: α-inflation – the sus­pi­cion begins to mount Helmut 2014-07-21 02:04 
  • EMA: α-inflation – the sus­pi­cion begins to mount ElMaestro 2014-07-21 09:24
    • Why simulate a simple AB|BA at all? Helmut 2014-07-21 16:14
      • Why simulate a simple AB|BA at all? ElMaestro 2014-07-21 20:50
        • Fancy smoothing? Helmut 2014-07-21 23:13
          • Arbitrary smoothing? d_labes 2014-07-22 08:43
            • Noise… Helmut 2014-07-22 13:31
              • TSD Japonica… d_labes 2014-07-22 16:06
                • TSD Japonica… Helmut 2014-07-22 17:50
              • Noise debuggedd_labes 2014-07-24 13:47
                • Noise debugged Helmut 2014-07-24 15:07
                  • Shit happens d_labes 2014-07-24 16:09
        • Commentary d_labes 2014-07-22 08:18
          • Commentary nobody 2014-09-15 08:24
            • Commentary Helmut 2014-09-15 10:12
        • IBE/PBE = Two-Stage Helmut 2014-09-29 03:33
          • IBE/PBE = Two-Stage ElMaestro 2014-09-29 15:16
            • Sequential Design = Inflation likely… Helmut 2014-09-30 15:03