Bioequivalence and Bioavailability Forum • Stability ?

Stability ? [RSABE / ABEL]

posted by Helmut – Vienna, Austria, 2014-04-07 21:39 (4054 d 16:01 ago) – Posting: # 12791
Views: 13,427

Dear Ohlbe & Pash,

❝ Could this be due to a stability issue ?

Very good point! I’m traveling, so I don’t have access to all my data. Both 5-ASA and N-acetyl-5-ASA are stable at <-70 ℃ for five months and 24 hours at room temperature (anticoagulant heparin). Since we never stored samples at <-70 ℃ for fun, for sure there were problems at -20 ℃.

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Complete thread:

Zero concentrations – all samples – full replicate pash413 2014-04-05 14:56
- Zero concentrations – all samples – full replicate ElMaestro 2014-04-05 20:17
- Zero concentrations – all samples – full replicate luvblooms 2014-04-07 07:47
  - serious risk to public health Dr_Dan 2014-04-07 08:35
  - Zero concentrations – all samples – full replicate pash413 2014-04-07 08:37
    - Zero concentrations – all samples – full replicate Helmut 2014-04-07 09:01
      - Zero concentrations – all samples – full replicate pash413 2014-04-07 09:30
        
        Imputation and BE/TE ElMaestro 2014-04-07 12:14
      - Zero concentrations – all samples – full replicate nobody 2014-04-07 09:31
    - Zero concentrations – all samples – full replicate luvblooms 2014-04-07 11:50
      - Zero concentrations – all samples – full replicate Mahesh M 2014-04-07 12:23
      - Zero concentrations – all samples – full replicate jag009 2014-04-07 16:18
    - Zero concentrations – all samples – full replicate jag009 2014-04-07 15:29
- Stability ? Ohlbe 2014-04-07 18:23
  - Stability ?Helmut 2014-04-07 19:39
    - Stability ? pash413 2014-04-09 13:00
      - Stability ? Mahesh M 2014-04-09 14:51
      - Stability ? Ohlbe 2014-04-09 16:31