Bioequivalence and Bioavailability Forum • Carry-over

Carry-over [RSABE / ABEL]

posted by Shuanghe – Spain, 2014-02-10 18:11 (4519 d 18:30 ago) – Posting: # 12383
Views: 19,461

Hi Lucas,

❝ ...then how am I supposed to know when a carry-over effect took place...

check predose concentration on period 2 or later periods if you have > 2 periods. In general carryover shouldn't be any problem if your washout is long enough.

—
All the best,
Shuanghe

Complete thread:

Sample size calculation for R-SABE Lucas 2014-02-07 11:41
- EMA’s ABEL Helmut 2014-02-07 14:21
  - EMA’s ABEL Lucas 2014-02-07 16:49
    - Carry-over Helmut 2014-02-07 17:12
      - Carry-over Lucas 2014-02-07 17:42
        
        Carry-overShuanghe 2014-02-10 17:11
- PowerTOST and Sample size estimation for R-SABE d_labes 2014-02-07 14:37
  - PowerTOST and Sample size estimation for R-SABE kumarnaidu 2014-04-18 13:38
    - PowerTOST and Sample size estimation for R-SABE Dr_Dan 2014-04-18 19:29
      - PowerTOST and Sample size estimation for R-SABE kumarnaidu 2014-04-19 06:04
  - PowerTOST and Sample size estimation for R-SABE Astea 2015-06-25 01:14
    - Sample size for scABEL/RSABE vs. conventional ABE d_labes 2015-06-25 09:19
    - PowerTOST and Sample size estimation for R-SABE mittyri 2015-06-25 10:43
      - PowerTOST and Sample size estimation for R-SABE Astea 2015-06-25 13:54
        
        Scaled ABE d_labes 2015-06-25 14:04