Bioequivalence and Bioavailability Forum • Carry-over

Carry-over [RSABE / ABEL]

posted by Lucas – Brazil, 2014-02-07 18:42 (4113 d 10:10 ago) – Posting: # 12371
Views: 16,941

Helmut

❝ May I ask which code you are using?

We use Pharsight's Phoenix, and not R or SAS.

❝ If there is a true sequence effect (or more precisely unequal carry-over) you can’t do anything in the analysis. The treatment estimate will be biased.

Yes, I understand that, but did not get why it should be withdrawn from the model, because then how am I supposed to know when a carry-over effect took place... Well that's a discussion for another topic and probably has already been done here. There is no need for answering that again here, I'll just search the forum.
Thanks again guys, see ya.

Complete thread:

Sample size calculation for R-SABE Lucas 2014-02-07 11:41
- EMA’s ABEL Helmut 2014-02-07 14:21
  - EMA’s ABEL Lucas 2014-02-07 16:49
    - Carry-over Helmut 2014-02-07 17:12
      - Carry-overLucas 2014-02-07 17:42
        
        Carry-over Shuanghe 2014-02-10 17:11
- PowerTOST and Sample size estimation for R-SABE d_labes 2014-02-07 14:37
  - PowerTOST and Sample size estimation for R-SABE kumarnaidu 2014-04-18 13:38
    - PowerTOST and Sample size estimation for R-SABE Dr_Dan 2014-04-18 19:29
      - PowerTOST and Sample size estimation for R-SABE kumarnaidu 2014-04-19 06:04
  - PowerTOST and Sample size estimation for R-SABE Astea 2015-06-25 01:14
    - Sample size for scABEL/RSABE vs. conventional ABE d_labes 2015-06-25 09:19
    - PowerTOST and Sample size estimation for R-SABE mittyri 2015-06-25 10:43
      - PowerTOST and Sample size estimation for R-SABE Astea 2015-06-25 13:54
        
        Scaled ABE d_labes 2015-06-25 14:04