Bioequivalence and Bioavailability Forum • Sims & evaluation

Sims & evaluation [RSABE / ABEL]

posted by ElMaestro – Denmark, 2013-08-31 16:11 (4681 d 21:34 ago) – Posting: # 11398
Views: 12,462
(edited on 2013-08-31 17:04)

Dear d_labes,

❝ EMA ANOVA:Sims according to the 'all effects fixed' doctrine as discussed here.

❝ • Evaluation of the replicate design with the same ANOVA as for the 2x2x2 crossover. Point estimator and its 90% CI via LSMeans difference.

OK... lemmefink....if you apply one lm (or one anova) then it must imply that you are working with one error term. Where TRT and RTR imply two different error mean squares, as you referenced earlier, I think we cannot do both TRT data and RTR data in one model if the model has only one error term. It must be either one model with (at least) two error terms (aka. mixed) or two models with one error term in order to cover both groups.

—
Pass or fail!
ElMaestro

Complete thread:

3-per, 2-trt designs and estimation of intra-subj. variance ElMaestro 2013-08-12 19:54
- 3-per, 2-trt designs and estimation of intra-subj. variance Dr_Dan 2013-08-13 10:11
  - 3-per, 2-trt designs and estimation of intra-subj. variance ElMaestro 2013-08-13 15:00
    - TRT|RTR rulez! Helmut 2013-08-13 18:23
      - TRT|RTR rulez? Really? d_labes 2013-08-14 08:16
        
        TRT|RTR rulez? Really? Yes. ElMaestro 2013-08-14 11:29
        
        TRT|RTR rulez? Really? No. d_labes 2013-08-14 13:34
        
        TRT|RTR rulez? Really? No. ElMaestro 2013-08-14 14:25
        
        TRT|RTR Lost in formulas. d_labes 2013-08-14 16:35
        
        TRT|RTR rulez? References Helmut 2013-08-14 13:44
        
        References László & László d_labes 2013-08-14 19:12
        
        Heteroscedasticity Helmut 2013-08-17 17:33
        
        Heteroscedasticity: TRT|RTR rulez! d_labes 2013-08-29 16:45
        
        Heteroscedasticity: TRT|RTR rulez! ElMaestro 2013-08-29 17:50
        
        Sims & evaluation d_labes 2013-08-30 09:16
        
        Sims & evaluationElMaestro 2013-08-31 14:11
        
        Evaluation subtleties d_labes 2013-08-31 17:20