Bioequivalence and Bioavailability Forum • 4way full replicate SAS routine from FDA guidance

4way full replicate SAS routine from FDA guidance [RSABE / ABEL]

posted by jag009 – NJ, 2013-04-08 22:18 (4827 d 15:39 ago) – Posting: # 10373
Views: 6,853

Hi,

Does anyone have trouble trying out the 4way full replicate SAS code from FDA's progesterone guidance? I tried it with the EMEA 4-way datasets but I am stuck at the merging routine for "test1 test2 ref1 ref2" and the ilat and dlat calculation.

Determine Iij andDij
data scavbe;
merge test1 test2 ref1 ref2;
by seq subj;
ilat=0.5*(lat1t+lat2t-lat1r-lat2r);
dlat=lat1r-lat2r;
run;

For some reason SAS won't compute ilat and dlat.

Thanks
John

Edit: Category changed. [Helmut]

Complete thread:

4way full replicate SAS routine from FDA guidancejag009 2013-04-08 20:18
- Merging problems? Helmut 2013-04-09 02:58
  - Merging problems? jag009 2013-04-09 20:12
    - critbound? Helmut 2013-04-10 17:32
      - critbound? jag009 2013-04-10 21:22