Log in
RegisterAdaptive BE: concepts [Two-Stage / GS Designs]
Dear Martin!
I didn't understand your Concept 2
.
How comes the "Go for early stopping" into the picture?
❝ Concept 2: Go for early stopping by planning a study with a type I error of 2.5% and a target power of >80% leading to n subjects in the first stage:
❝ - Early stopping (best case as expected)
❝ - Calculate sample size for 2nd stage (try to rescue the study when the a-priori made assumptions were wrong)
I didn't understand your Concept 2
.How comes the "Go for early stopping" into the picture?
—
Regards,
Detlew
Regards,
Detlew
Complete thread:
- Adaptive BE: concepts martin 2012-07-11 20:31
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Adaptive BE: conceptsd_labes 2012-07-12 11:53
- Adaptive BE: concepts martin 2012-07-12 13:36
- Adaptive BE: conceptsd_labes 2012-07-12 11:53
Ing. Helmut Schütz