A rant [Two-Stage / GS Designs]

posted by Achievwin – US, 2024-08-28 04:16 (219 d 06:47 ago) – Posting: # 24166
Views: 1,515

I feel your pain, just curious if the two stage design went beyond 2x2 crossover or we are stuck in 1990s time? Any example how two stage adaptive design is applied/validated for parallel study or replicate design?

In case of parallel design what kind of statistical factor we need to use Potvin or Bonferroni and same for 4-period or 3-period replicate design?

Complete thread:

UA Flag
Activity
 Admin contact
23,413 posts in 4,924 threads, 1,670 registered users;
61 visitors (0 registered, 61 guests [including 3 identified bots]).
Forum time: 11:03 CEST (Europe/Vienna)

Nothing shows a lack of mathematical education more
than an overly precise calculation.    Carl Friedrich Gauß

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5