Bioequivalence and Bioavailability Forum • A place to start

A place to start [Two-Stage / GS Designs]

posted by ElMaestro – Denmark, 2017-11-12 22:43 (2779 d 02:59 ago) – Posting: # 17973
Views: 10,389

Hi Hötzi,

can you run a series of sims where you include "20 more subjects than necessary" in stage 2 where a stage 2 is called for?
Just to see how things look from that perspective.

—
Pass or fail!
ElMaestro

Complete thread:

Two PK metrics: Inflation of the Type I Error Helmut 2017-11-12 11:57
- Two PK metrics: Inflation of the Type I Error? d_labes 2017-11-12 17:46
- A place to startElMaestro 2017-11-12 21:43
  - A place to start? d_labes 2017-11-13 16:02
    - A place to start? Helmut 2017-11-13 16:51
      - Scientific gut feeling d_labes 2017-11-15 10:34
        
        Five minutes gone - power.tsd.2m() arose d_labes 2017-11-15 13:15
    - A better place to start. ElMaestro 2017-11-14 00:04
      - Nope Helmut 2017-11-14 00:21
        
        Nope nobody 2017-11-14 08:11
        I've meditated hard ElMaestro 2017-11-14 12:41