Bioequivalence and Bioavailability Forum

Histogram beast [Two-Stage / GS Designs]

posted by Helmut  – Vienna, Austria, 2015-06-09 17:24 (3666 d 08:26 ago) – Posting: # 14934
Views: 19,578

Dear Detlew!

❝ A better way would be to return the vector of ntot (your suggestion in our correspondence) …

Well, you convinced me that it doesn’t makes sense to return such a large vector (con­sisting easily of 1 mio elements).

❝ … instead of some histogram-data with standard settings.

Maybe. Maybe not. IMHO, it is good practice to select the number of bins based on the range of data. See help(nclass.Sturges)

❝ That would give you all freedom to design the histogram to your needs.

True.

❝ Example: 100 bins in the histogram

IMHO, that’s a bit over the top.
I guess that 50 are more than enough to prescind the first stage and show the log-dis­tri­bution of sample sizes in the second stage. Well, log="x" rightly throws warnings since this is not a histogram proper any more!

❝ Note the pronounced and outstanding role of N=24, the sample size for stage 1. Not so clear seen in your pictures above for OBF or Zheng. Partly now also seen for HP.

Righty-right! With some tweaks:

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

• Does unequal alpha distribution make sense? Dr_Dan 2015-05-19 08:29 
  • Maybe; but watch the TIE! Helmut 2015-05-28 15:04
    • Advantages d_labes 2015-06-05 09:35
      • Advantages ElMaestro 2015-06-05 10:07
        • Advantages – performance measure d_labes 2015-06-05 11:21
          • Advantages – performance measure Helmut 2015-06-05 13:29
            • Advantages – performance measure d_labes 2015-06-05 21:27
              • Advantages – performance measure Helmut 2015-06-05 23:29
                • Histogram wonder d_labes 2015-06-06 12:58
                  • Histogram charlatanry Helmut 2015-06-09 13:43
                    • Histogram beauty d_labes 2015-06-09 14:55
                      • Histogram beastHelmut 2015-06-09 15:24
  • Does unequal alpha distribution make sense? Dr_Dan 2015-05-29 08:33
    • Does unequal alpha distribution make sense? ElMaestro 2015-05-29 09:31
      • Does unequal alpha distribution make sense? nobody 2015-05-29 12:56
        • Old beliefs die hard Helmut 2015-05-29 13:27
          • Old beliefs die hard nobody 2015-05-29 13:41
            • Old beliefs die hard Helmut 2015-05-29 18:08
              • Old beliefs die hard ElMaestro 2015-05-29 18:57
                • Old beliefs die hard nobody 2015-05-29 20:06
                • ♩ ♪♫♬`·.¸¸.·´`·.¸¸. Helmut 2015-06-02 01:52
                  • TSD only an option in ex­ceptional cases Dr_Dan 2015-06-02 08:00
                    • TSD only an option in ex­ceptional cases nobody 2015-06-02 09:23
                      • OT Helmut 2015-06-02 12:07
                        • OT nobody 2015-06-02 12:41
  • Banana splits Helmut 2015-06-02 00:48