Bioequivalence and Bioavailability Forum • Group effects EMA

Group effects EMA [Two-Stage / GS Designs]

posted by Helmut – Vienna, Austria, 2014-10-01 15:24 (4272 d 12:56 ago) – Posting: # 13632
Views: 49,318

Hi Mittyri,

I agree with our Master. Simple example:

group subject period sequence treatment response

  1      1       1       RT       R        100

  1      1       2       RT       T         95

  1      2       1       TR       T         95

  1      2       2       TR       R         90

  1      3       1       RT       R        105

  1      3       2       RT       T        100

  1      4       1       TR       T        105

  1      4       2       TR       R        100

  2      5       1       RT       R        100

  2      5       2       RT       T         95

  2      6       1       TR       T         95

  2      6       2       TR       R         90

  2      7       1       RT       R         90

  2      7       2       RT       T         85

  2      8       1       TR       T         85

  2      8       2       TR       R         90

sequence+period+formulation+subject(sequence) 98.65% [96.05–101.32%]
sequence+period+formulation+group+subject(sequence) 98.65% [96.05–101.32%]

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

Potvin C in the EU Helmut 2013-04-16 17:40
- Potvin C in the EU ElMaestro 2013-04-17 02:31
  - Potvin C in the EU Helmut 2013-04-17 12:23
    - 2 Groups model FDA d_labes 2013-04-17 13:10
      - 2 Groups model FDA Helmut 2013-04-17 16:37
        
        Group effects obsolete? d_labes 2013-04-18 09:55
        
        Group effects FDA/EMA Helmut 2013-04-19 14:34
        
        Group effects FDA/EMA mittyri 2014-08-21 15:34
        
        Group effects FDA/EMA ElMaestro 2014-08-21 17:31
        
        Group effects EMA mittyri 2014-10-01 11:25
        
        Group effects EMA ElMaestro 2014-10-01 11:31
        Group effects EMAHelmut 2014-10-01 13:24
        
        Group effects EMA VStus 2016-10-06 22:06
        
        Group effects EMA ElMaestro 2016-10-07 12:45
        
        Group effects EMA mittyri 2016-10-07 15:06
        
        Fixed effects model with Group term mittyri 2016-10-09 13:27
        
        Fixed effects model: changing the F, p values mittyri 2016-10-10 18:33
        
        Fixed effects model: changing the F, p values ElMaestro 2016-10-10 20:10
        
        Fixed effects model: changing the F, p values Helmut 2016-10-11 00:17
        Holy War of type III d_labes 2016-10-11 13:17
        
        Significance of Group effect in Russia: why the type III is so 'important' mittyri 2016-10-11 15:07
        
        Fixed effects model: changing the F, p values zizou 2016-10-11 01:06
        
        FDA group model in R mittyri 2016-10-11 13:43
        
        FDA group model in R ElMaestro 2016-10-12 01:07
        FDA group model in R VStus 2016-10-17 15:32
        
        FDA group model in R ElMaestro 2016-10-17 18:58
        
        FDA group model in R VStus 2016-10-20 13:57
        
        Fixed effects model with Group term VStus 2016-10-20 13:54
        
        Group effects FDA/EMA zizou 2016-12-31 02:54
        
        Group effects FDA/EMA Helmut 2017-06-03 14:57
        
        2 Groups model FDA hiren379 2013-08-22 14:32
        
        Homework Helmut 2013-08-23 11:53