WinNonlin 5.2.1 setup [Two-Stage / GS Designs]
Hi Helmut,
Here in our company WinNonlin 5.2.1 is installed, So i have to do analysis using the same version. Done the analysis, but the problem is that, 94.12% confidence interval values are coming same when subject(sequence) is treated as fixed effect and another with random effect.
Could be please explain why this happened?
I have attached the screen shot of the settings used.
Thank you in advance.
![[image]](img/uploaded/image91.jpg)
Edit: Subject line changed. [Helmut]
Here in our company WinNonlin 5.2.1 is installed, So i have to do analysis using the same version. Done the analysis, but the problem is that, 94.12% confidence interval values are coming same when subject(sequence) is treated as fixed effect and another with random effect.
Could be please explain why this happened?
I have attached the screen shot of the settings used.
Thank you in advance.
![[image]](img/uploaded/image91.jpg)
Edit: Subject line changed. [Helmut]
—
Regards,
MGR
Regards,
MGR
Complete thread:
- SAS code for 2-stage design MGR 2014-05-22 07:45
- SAS code for 2-stage design d_labes 2014-05-22 08:17
- Phoenix/WinNonlin code Helmut 2014-05-22 12:24
- maybe R too? yjlee168 2014-05-23 21:17
- RSABE/ABEL in a TSD: Science fiction Helmut 2014-05-23 22:39
- WinNonlin 5.2.1 setupMGR 2014-07-02 07:08
- outdated software; mixed vs. fixed effects Helmut 2014-07-02 10:40
- outdated software; mixed vs. fixed effects MGR 2014-07-03 06:32
- outdated software; mixed vs. fixed effects Helmut 2014-07-02 10:40
- maybe R too? yjlee168 2014-05-23 21:17