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RegisterPotvin’s TSDs in the EU [Two-Stage / GS Designs]
Hi,
When I saw this I knew something bad gonna happen.
OK, that's not what I was expecting.
I don't know if Elmaestro and I were reading the same thing but the hidden line I've got is that:
ok, you are "lucky" that your formulation screwed so you have to stop after stage 1; if you go to stage 2 and the result "appears" OK I'm gonna ask about the alpha inflation, higher patient risk, etc etc...
How's that "... occasionally even Austrians say something meaningful. "
❝ .. is principally acceptable. ...
When I saw this I knew something bad gonna happen.
❝ ... However, as the study was stopped for inequivalence, any further considerations on type I error control become obsolete.
OK, that's not what I was expecting.
I don't know if Elmaestro and I were reading the same thing but the hidden line I've got is that:
ok, you are "lucky" that your formulation screwed so you have to stop after stage 1; if you go to stage 2 and the result "appears" OK I'm gonna ask about the alpha inflation, higher patient risk, etc etc...
How's that "... occasionally even Austrians say something meaningful. "
—
All the best,
Shuanghe
All the best,
Shuanghe
Complete thread:
- Potvin’s TSDs in the EU Helmut 2013-10-30 18:48
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Partial thumbs up to AGES ElMaestro 2013-10-30 19:26
- AGES & numeric precision Helmut 2013-10-31 15:01
- AGES & numeric precision ElMaestro 2013-10-31 18:16
- AGES & numeric precision Helmut 2013-10-31 15:01
- Potvin’s TSDs in the EUShuanghe 2013-10-31 10:48
- Exegesis Helmut 2013-10-31 12:51
- Potvin’s TSDs in the EU ElMaestro 2013-10-31 13:04
- Partial thumbs up to AGES ElMaestro 2013-10-30 19:26
Ing. Helmut Schütz